Biomedica provides a comprehensive product portfolio in the field of Antimicrobial Resistance.

Antimicrobial Resistance (AMR) is the ability of a microorganism (e.g. bacterium, fungus or parasite) to resist the action of an antimicrobial agent. The World Health Organization (WHO) has included AMR as one of the top ten threats to global health in 2019 (WHO 2019).
Today, we live in a time when more and more diseases, including respiratory tract infections, sexually transmitted infections and urinary tract infections, do not respond to drug treatment and life-saving medical procedures are becoming much riskier due to the threat of untreatable infections.
The selective pressure created by the broad use of antibiotics in agriculture, livestock, veterinary and human medical practices has contributed to the current antibiotic resistance crisis - the expansion of multidrug resistant organisms (MDROs) on a global level.

Addressing the rising threat of AMR requires therefore a multidisciplinary approach. One Health Strategy integrates human, veterinary, but also environmental, aquatic, and wildlife issues into current approaches.
AMR is a global crisis. There is no time to wait.

  Antimicrobial Susceptibility Testing

  Molecular Assays for Active MDRO Screening

MRSA- methicillin-resistant Staphylococcus aureus carriage

VRE- vancomycin-resistant Enterococci carriage

CRE- carbapenem-resistant Enterobacteriaceae

  • A qualitative, on-demand real-time PCR test for the detection and differentiation of KPC, NDM, VIM, OXA-48 and IMP in 48 minutes
    Cepheid Xpert Carba-R

ESBL- Extended-Spectrum Beta-Lactamase producing bacteria carriage

Colistin resistant Enterobacteriaceae colonization

  Molecular Assays for Diagnosing Antibiotic Resistant Infections

Panels for diagnosis of sepsis-causing pathogens and resistance markers

Detection of MRSA infections

Rifampicin and Isoniazid-resistant MTB infections

  • Combined with the frontline test Xpert MTB/RIF Ultra, Xpert MTB/XDR detects mutations associated with drug resistance towards Isoniazid, Fluoroquinolones, Second-Line Injectable Drugs and Ethionamide
    Xpert MTB/XDR

Clarithromycin-resistant Helicobacter pylori infections

Drug-resistant Sexually Transmitted Infections

  • The first molecular CE_IVD test to detect Mycoplasma genitalium and macrolide resistance markers
    SpeeDx ResistancePlus MG


  Rapid detection of Antibiotic Resistance Markers from culture and positive  blood culture

NG Biotech develops multiplex rapid tests in lateral flow format based on the use of specific monoclonal antibodies.
All tests are validated at the French National Reference Center on Antimicrobial Resistance (AMR).

  • Rapid detection of group 1 CTX-M β-lactamases (ESBL)
    NG-Test CTX-M
  • Detection of CTX-M-1, CTX-M-2, CTX-M-8, CTX-M-9 and CTX-M-25 (the main CTX-M groups) with a high negative predictive value – ideal for screening
  • Rapid detection and differentiation of KPC, OXA, VIM, IMP and NDM
    NG-Test CARBA5
  • Rapid and visual immunoassay for the detection of MCR-1 mediated colistin resistance
    NG-Test MCR-1

Complete Overview: Please Click

  Quality Control in Molecular Testing for MDRO

Vircell AmpliRun are non-infectious complete genome preparations that can be used for full process control of any molecular testing.

  • AmpliRun Staphylococcus aureus mecA+ DNA control
  • AmpliRun Enterococcus faecalis (vanB) DNA control
  • AmpliRun Enterococcus faecium (vanA) DNA control
    Complete Overview: Please Click

Microbiologics Helix Elite Molecular standards are single or multi parameter molecular controls.

  • Helix Elite CRE Control Panel - Inactivated Swab. IMP, KPC-3, NDM-1, OXA-48, VIM-1, Metallo-beta-lactamase positive
  • Helix Elite MRSA - Inactivated Swab
  • Helix Elite Enterococcus faecium (vanA) positive control swabs, Enterococcus faecalis negative control swabs